Puppies must be vaccinated after weaning, i.e when they are 45-50 days old, that is the age in which they can develop enough antibodies with vaccination.
50 days: Parvovirus-Coronavirus.
65 days: Distemper-Hepatitis-Parvovirus-Adenovirus.
80-90 days: Distemper-Hepatitis-Parvovirus-Leptospirosis.
6 months: Anti-rabies (repeat every 12 months from that date on)
12 months: Distemper-Hepatitis-Parvovirus-Leptospirosis (repeat every 12 months from that date on)
Vaccine against Leptospirosis must be repeated every six months.